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  Background: Physical train has been long recognized for its therapeutic effects on depressive disorders, however the underlying
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  Ex. The variations in useful brain adjustments
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  resonance imaging (fMRI). Results: The results showed that VWR train significantly reversed the CUMS-induced behavioral abnormalities.
  Base on the fMRI amplitude of low-frequency fluctuation (ALFF) analysis, we found that VWR train may restore the CUMS-induced excessive Bold activation in elements of limbic system, corresponding to cortex, hippocampus and corpus callosum.
  
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  cerebellum anterior lobe, thalamus, midbrain, and pontine.
  Most of those areas are concerned in mood-regulating circuit, suggesting dysfunction of the circuit in CUMS
  model of depression, and VWR train could modify the mood-regulating circuit.
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